Ketamine/Esketamine Administration
Off-label use vs FDA-approved nasal sprays for TRD.
Monitoring requirements, dissociation management, and maintaining response in TRD.
Clinical Applications
This protocol integrates findings from recent randomized controlled trials (RCTs). We advise cross-referencing with your local institutional guidelines and the associated clinical tools to calculate specific dosing parameters or risk scores.
Frequently Asked Questions
Q: When should this protocol be reconsidered?
A: If the patient exhibits significant hepatic or renal impairment, requiring immediate dose adjustments. See the Pharmacology Guide for CYP450 considerations.